Second-seeded Campbell went on a 14-2 run and went on to outscore Hillgrove 24-12 in the second quarter. The Lady Spartans led the rest of the game, though the fourth-seeded Lady Hawks were able to get within one point late in the fourth quarter.
"It's a great thing for us to win this region since there are some really good teams in the region," Campbell coach Randy McClure said. "Hillgrove is a very good team and it was a tough game."
It is the first region title in four years for Campbell (22-6), which won the 5AAAAA crown in 2007.
Chakecia Miller scored 20 points, while Erica Norwood added 13 and Baylee Hawkins had 10 to lead Campbell. The Lady Spartans will be the top seed when they host Newton, the No. 4 seed from Region 2AAAAA, on Friday in the first round state tournament.
Reka Hall scored 18 points, while Mackenzie Engram added 11 and Celina Rodrigo 10 for Hillgrove (20-5), which will host third-seeded Luella in the first round.
Hillgrove led 17-14 at the end of the first quarter and was up 21-16 with 7:01 remaining in the first half when Campbell came back with a 3-pointer by Hawkins and layup by Jaleesea Phillips to tie the game at 21-all with 6:25 left.
Hall drove in for a layup to give the lead back to Hillgrove, 23-21 with 6:07 left, but that would be the last lead of the game for the Lady Hawks. Miller soon nailed a 3-pointer to put Campbell back in front, 24-23, with 5:40 left.
Miller hit a jumper to increase Campbell's lead to 26-23 with 4:51 left in the first half and, after Rodrigo helped Hillgrove cut its deficit to 26-25 with a jumper, Norwood hit a 3-pointer, D'Asia Cain drove in for a transition layup and Miller scored on a layup and then later sank two free throws to give the Lady Spartans a 35-25 advantage with 2:57 left.
Campbell went on to lead 38-29 at halftime and 47-34 with 5:27 remaining in the third quarter, before Hillgrove went on a 11-3 run to finish the period trailing only 50-45.
The Lady Hawks cut Campbell's lead even more to 53-52 with 2:31 remaining in the game, but the Lady Spartans - going 8-for-8 from the free-throw line down the stretch and 9-for-10 in the fourth quarter - went on an 8-2 run to close out the win.