Monday, the school announced the former Harrison Hoya is foregoing his senior season and will make himself eligible for April's NFL Draft.
The deadline to enter the draft was last Saturday.
Adams' decision follows similar announcements from defensive lineman Nick Fairley and Heisman Trophy winning quarterback Cam Newton, which made their intentions to go to the NFL known last weekend.
But while Fairley and Newton are expected to hear their names called in the first round, Adams, who led the Tigers in receiving the last two seasons, may have to wait until Day 2 or Day 3 of the draft.
The majority of draft experts say the 6-foot-3, 185 pound Adams will go in the later rounds because of a draft class full of talent at the wide receiver position including, Georgia's A.J. Green, Alabama's Julio Jones, Oklahoma State's Justin Blackmon and Oklahoma's Ryan Broyles, all juniors which are receiving most of the early publicity.
The 21 year-old Adams, who has 4.5 speed, leaves Auburn after two solid seasons. As a sophomore, he caught a school record 60 passes for 997 yards and 10 touchdowns. Adams followed that this year with 52 receptions for 963 yards and seven touchdowns.
For his career, he ends as the Tigers sixth all-time leading pass catcher in both receptions (115) and receiving yards (1,978) and is third in touchdown catches with 17.
Adams also set an SEC championship game record with 217 yards receiving against South Carolina.
Efforts to reach Adams for comment were unsuccessful.